ASUS has announced the launch of the ExpertCenter PN54-S1, a new mini PC designed for business and commercial use. Housed in a compact 0.6-litre premium aluminum chassis, this device is engineered for reliable 24/7 operation and is powered by the latest AMD Ryzen 200 Series processors to handle everyday workloads with efficiency.
The ExpertCenter PN54-S1 is optimized for productivity and AI-driven tasks. The new Ryzen 200 Series processor is built on the AMD Zen 4 architecture and features up to eight CPU cores, supporting up to 64GB of DDR5-5600MHz memory for low-latency multitasking. The processor also provides up to 16 AI TOPS, enabling the mini PC to handle local AI operations such as real-time translation and image enhancement responsively. For graphics, the PN54-S1 is equipped with AMD Radeon 780M graphics based on the RDNA3 architecture, which delivers a 54% performance improvement over the previous-generation PN53, making it ideal for AI-assisted graphics generation and content creation.

Connectivity is extensive, with a total of six USB ports, including a versatile rear USB4 Type-C port that supports DisplayPort 2.1, 40Gbps data transfer, and 100W power delivery. The PN54-S1 can drive up to four 4K displays simultaneously, making it a flexible solution for various business setups. It also features the latest wireless networking options, with configurations for either WiFi 7 or WiFi 6E, alongside a 2.5G LAN port for fast wired connections.
ASUS has integrated several enterprise-grade features into the PN54-S1. Security is addressed with a built-in fingerprint sensor for biometric logins and a discrete TPM 2.0 module for hardware-level key management that complies with Windows 11 standards. For large-scale IT deployments, the optional ASUS Control Centre software provides a centralised platform for device management. The mini PC is built for longevity, meeting multiple US MIL-STD-810H standards for durability against extreme temperatures, altitude, and humidity. Its toolless design allows for easy memory and storage upgrades.
Pricing and Availability
The ASUS ExpertCenter PN54-S1 Mini PC will be available globally starting from the fourth quarter of 2025. ASUS has not yet announced local pricing and specific configurations for the Malaysian market. The device will be offered in various configurations, including fully-equipped systems with Windows 11 pre-installed and as a barebone kit for users who prefer to install their own memory, storage, and operating system.